Message Number: FHL5054 | New FHL Archives Search
From: "Sukie Crandall"
Date: 2008-05-30 13:53:57 UTC
Subject: [ferrethealth] Re: Adrenal disease, surgery vs Lupron.

Wow. I'll have to look for that article and abstract. Sadly,
it is not in PubMed.

Just from personal experience and our vet's experience it
is better locally than it used to be but such high error
rates in that study are a real concern.

Long ago (long enough ago that Lysodren was used and
that now abandoned approach was actually new) we had a
male who looked like a bilateral on ultrasound but he instead
had lymphoma in the right adrenal and his left adrenal was
clean despite what the ultrasound said.

(The Lysodren wound up atrophying his good adrenal
so even though Pred and removal of his right adrenal kept
his lymphoma under control for 14 months he did wind up
being one of the first ferrets on Fludrocort (before publication
of the Colorado study which was probably happening about
the same time independently).

Thank you so very, very much for yet another chance to

To each tool and technique its best applications... Thank
goodness for ultrasounds for some other things such as
cardiomyopathy and ultrasound guided aspirations for

--- In, AFERRETVET@... wrote:
> Hi Tressie
> In your post you mentioned your vet using ultrasound to
> diagnose adrenal gland disease. You are right, this is
> not an accurate way to diagnose adrenal gland disease.
> In a recent adrenal article from Colorado State University's
> vet school, 18 adrenal ferrets had an ultrasound before surgery.
> 5 of the 18 ferrets had a false negative (ie they had adrenal disease
> even though the ultrasound did not pick it up) and 6 of the 18 ferrets
> had an incorrect identification of the adrenal gland that was affected
> (ie ultrasound thought it was one adrenal gland but surgery showed
> it was the other adrenal gland). That is 11 of 18 (61%) that had an
> incorrect result. Thus as I have been saying for at least a decade,
> Ultrasound is not a good way to diagnose adrenal gland disease.
> {Yes, the skill level and experience of the ultrasounder and the quality
> and size of the probe makes a difference, but this was an article
> from a vet school with experts using a good ultrasound machine.}
> Losing hair on the tail, and aggressive behavior are both signs of adrenal
> gland disease.
> As far as Deslorelin, do not use the short acting horse product.
> The long lasting implant (Suprelorin) for dogs and cats is what you want.
> Unfortunately it is not available in the US yet.
> Hope that helps,
> Jerry Murray, DVM


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