From:
Sukie Crandall
Date: 2008-06-27 22:14:28 UTC
Subject: [ferrethealth] Intra-abdominal leiomyosarcoma
To: fhl <ferrethealth@yahoogroups.com>
Begin Quoted Abstract
J Vet Med Sci. 2008 May;70(5):513-5.
Intra-abdominal leiomyosarcoma in a ferret (Mustela putorius Furo):
histopathological and immunohistochemical characterization.
Pezzolato M, Varello K, Mascarino D, Bozzato E, Vascellari M, Bozzetta
E.
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle
d'Aosta, Area Neuroscienze e Genetica, Laboratorio di
Immunoistopatologia, Torino, Italy. istopatologia.ufficio@izsto.it
A 5 years old female ferret with an abdominal palpable mass confirmed
at echo-graphic examination died during an explorative laparotomy. A
single lymph-node-like nodule was found adjacent to the intestinal
loops. The round mass well circumscribed, solid and white,
histologically, at low magnification, appeared encapsulated and built
up by a population of atypical spindle cells arranged in interwoven
fascicles. The cells had high anisocytosis degree, moderate mitotic
activity and prominent nucleoli. A central area of necrosis was
present. To characterise the tumour immunohistochemically cytokeratin,
vimentin, S-100, melan-A, vWF, desmin, actin and alpha-actin were
applied. Neoplastic cells resulted positive to vimentin, actin and
alpha-actin. Based on the histological and immunohistological pattern
a diagnosis of leiomyosarcoma was made.
PMID: 18525177
END QUOTE
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Non-text portions of this message have been removed]
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