Message Number: FHL5478 | New FHL Archives Search
From: "hillbabe26"
Date: 2008-07-09 20:00:35 UTC
Subject: [ferrethealth] Pre-tx with inj. Benedryl for vaccines?

I just experienced my first vaccine reaction with my ferret Bandit
(2+yo MF male) to the IMRAB3 rabbies vaccine.

He vomited repeatedly and was a bit droopy. They pretreated with inj.
Benadryl and after the reaction was observed, he was treated with
additional Benadryl and Dexamethesone (I don't have the exact dose
info in front of me, I assume it was a standard tx protocol) and
sub-cue fluids (apparently he felt healthy enough to rip out the IV
lines, twice).

I am planning to go forward with his next vaccination (for CD) and may
try the rabies again next year with a more intensive prophylactic
regimen (assuming the next jab goes well).

I looked in the archives and googled for information about vaccine
reactions, and have some additional questions.

1) There are some anecdotes in the archives of ferts reacting to the
pre-jab Benadryl itself, so would not pre-treating or treating with
Dex alone be a better strategy for the distemper vaccination? (in case
it was the benadryl he was reacting to? or would his tolerating the
additional doses of benadryl after reaction indicate that it was not
the benadryl??)

2) Is Merial's Purevax CD still number one for reduced reaction risks?

3) If there is a reaction to the CD or to next years IMRAB3, is it
true that a letter to health officials from the vet will excuse him
from future injections? or with local regulations changing so much
between regions, is this something only the local vet could answer
(I'm moving in a few months, so I will have to check the regs. after

Thanks in advance for any advice in how to go forward from here.

-Hillary (currently in MA, with Bandit and his shaven and bruised
forepaw who is otherwise back to his trouble-lovin' self)


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