From:
"Tressie"
Date: 2008-07-15 14:06:11 UTC
Subject: [ferrethealth] Re: Reaction to Biaxin
To: ferrethealth@yahoogroups.com
Dr. Williams,
Thank you for your prompt reply, which I have forwarded to my vet. I
just got back from seeing him BEFORE I got your post.
She was given sub-q hydration and an injection of Famotidine to
stabilize her. I was given several syringes to take home and inject
her with for the next several days. I have done this before myself
and am okay with doing it. I have been giving her the Sulcrate (.05
cc) twice a day and will up the dose as per your recommendations.
And will wait to put her back on the antibiotics once she's more
stable.
I had been feeding her a duck soup mix of A/D and chicken baby food
and will continue with that. Unfortunately, I had also allowed her
to eat kibble, but will remove the kibble from her diet.
Should I continue with the Famotidine injections as well as the
Sulcrate, she responds very well to the Famotidine, it seems to calm
her down. But if it might exacerbate things, I will not give that to
her?
Thank you sincerely for your timely advice.
Tressie
--- In ferrethealth@yahoogroups.com, "Bruce Williams, DVM"
<accupath@...> wrote:
>
> --- In ferrethealth@yahoogroups.com, "Tressie" <tressiedu@> wrote:
> >
> > I started her with the Biaxin, which she loved. Unfortunately,
an
> > hour later threw it all up with bloody mucous. My question,
could
> > she be allergic to it? I don't want to give it to her if it will
> > cause her to vomit.
> >
> > Help! Should I go back to the dreaded Metronidazole/Amoxicillin
> > combo??
>
>
> Dear Tressie:
>
> First of all, the prescribed treatments, both Biaxin/Amoxi and
> Metronidazole/Amoxi are not treatments for ulcers, but for
> Helicobacter, and I think in a 2-year-old with a bleeding ulcer,
> would not be my first choice.
>
> Ulcers are life-threatening, Helicobacter (which may be associated)
> is not. Are you still giving the Sucralfate, and if so, how often?
>
> In these cases, I generally don't give meds other than Sucralfate
and
> a bland diet for a number of days. The stress of giving a lot of
> meds actually worsens ulcers in ferrets, not improves them. We can
> always go back and treat the Helicobacter if we want.
>
> Sucralfate should be given at a dose of 75mg/lb 10 minutes before a
> meal, and no kibble! Duck Soup, baby food, a/d, Carnivore care -
> these are all good bland diets that supply nutrients in a highly
> digestible form.
>
> I'm much higher on Sucralfate than Pepcid, as many of these animals
> already have decreased stomach acid (a non-lethal problem in
animals
> with severe Helicobacter infection) and we can preserve acid
> production and improve digestion without totally blocking the
acid.
> The sucralfate forms a temporary patch for the ulcer, and the rest
is
> washed away downstream.
>
> I think it is unlikely you are seeing a reaction to the Biaxin - I
> think it is more likely that your ferret is vomiting due to pain
and
> nausea of an ulcer that it not-pre-coated with Sucralfate.
>
> With kindest regards,
>
> Bruce Williams, DVM
>
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