From:
Sukie Crandall
Date: 2008-10-10 04:35:44 UTC
Subject: [ferrethealth] abstract
To: fhl <ferrethealth@yahoogroups.com>
BEGIN QUOTE
J Vet Med Sci. 2008 Sep;70(9):893-8.
Cytomorphological and immunohistochemical features of lymphoma in
ferrets.
Onuma M, Kondo H, Ono S, Shibuya H, Sato T.
Onuma Animal Hospital.
Twenty ferrets with histopathologically diagnosed lymphoma were
classified cytomorphologically and immunohistochemically. According to
site of origin, multicentric, gastrointestinal, mediastinal and
cutaneous lymphomas accounted for 8 (40%), 9 (45%), 2 (10%) and 1 case
(5%), respectively. According to the National Cancer Institute Working
Formulation (NCI-WF), low-, high- and intermediate-grade lymphomas
accounted for 4 (20%), 4 (20%) and 12 cases (60%), respectively. The 4
low-grade lymphomas showed no mitotic figures, whereas all 4 high-
grade lymphomas exhibited >/= 3 mitotic figures (median,6). Higher
grade thus appears to be associated with a higher number of mitotic
figures. Immunohistochemical examination of 18 specimens, excluding 2
insufficient specimens, showed that 16 (88.9%) and 2 (11.1%) lymphomas
were of T-cell origin and B-cell origin, respectively. According to
the combination of the NCI-WF and immunophenotypes, all 4 low-grade
lymphomas (2 multicentric, 1 gastrointestinal, and 1 cutaneous
lymphoma) were classified as diffuse small lymphocytic lymphoma of T-
cell origin. Of the 12 intermediate-grade lymphomas (6 multicentric, 4
gastrointestinal, and 2 mediastinal lymphomas), 11 were classified as
diffuse mixed-cell lymphoma, and 1 as diffuse large cell lymphoma. Of
these 11 lymphomas, 2 (both multicentric) were of B-cell origin, 7 (3
multicentric, 3 gastrointestinal, 1 mediastinal) were of T-cell
origin, and 2 (1 multicentric, 1 mediastinal) were of unknown cell
origin. The remaining 1 lymphoma (gastrointestinal) was of T-cell
origin. All 4 high-grade lymphomas (gastrointestinal) were classified
as diffuse immunoblastic lymphoma of T-cell origin.
END QUOTE
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Non-text portions of this message have been removed]
------------------------------------
Yahoo! Groups Links
<*> To visit your group on the web, go to:
http://groups.yahoo.com/group/ferrethealth/
<*> Your email settings:
Individual Email | Traditional
<*> To change settings online go to:
http://groups.yahoo.com/group/ferrethealth/join
(Yahoo! ID required)
<*> To change settings via email:
mailto:ferrethealth-digest@yahoogroups.com
mailto:ferrethealth-fullfeatured@yahoogroups.com
<*> To unsubscribe from this group, send an email to:
ferrethealth-unsubscribe@yahoogroups.com
<*> Your use of Yahoo! Groups is subject to:
http://docs.yahoo.com/info/terms/