From:
"Sukie Crandall"
Date: 2008-12-16 13:46:10 UTC
Subject: [ferrethealth] Re: More about fibrosarcoma
To: ferrethealth@yahoogroups.com
Carol, if you look in the FHL Archives you will
see multiple vet posts that in cats punctures
themselves can set the stage for fibrosarcoma.
That had been looked at because they can
appear in cats (and in far fewer numbers) in
ferrets at injection sites. People thought that
it might be something that was being injected
that did it, but it was actually related to the
puncture and then inflammation, so a bite, or
a splinter, or a shoddy homemade cage with
sharp and loose wires, or...
http://ferrethealth.org/archive/FHL2003
BEGIN QUOTE
**You are partially correct, but not completely.
Sarcomas can happen in any species, and can be triggered by a number of
things. It is certainly true that among the things that can trigger a sarcoma to
occur, especially in cats, is an inflammatory reaction to a vaccine. But
sarcomas have been found that were triggered by foreign objects such as splinters
and grass awns, and that have no known trigger. I have seen sarcomas in dogs
and in cats that were clearly not possibly related to vaccination, as well as
those that were. The only sarcoma I have treated in a ferret was in a spot
that he had never received a vaccine in (I know as I had done all of his vaccines
and they were nowhere near the site of the tumor).**
Dr. Ruth
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EARLIER:
http://ferrethealth.org/archive/SG16177
BEGIN QUOTE
I have seen two, neither in an area where they could have possibly been due
to an injection. Cats do, as you stated, on occasion develop them from a
vaccine injection. However, cats have also been known to develop them from other
causes as well. Dogs also get fibrosarcomas.
It's something to think about, but so far I'm not convinced that in ferrets
it is related to injections.
Dr. Ruth
END QUOTE
2005:
http://ferrethealth.org/archive/SG16198
BEGIN QUOTE
Sorry to hear about the loss of your pet.
Can ferrets get sarcomas after an injection?
Yes, Very, Very rarely they can. I had a case report
of a vaccine injection site sarcoma in a pet ferret
published in JAVMA (213:955) back in 1998. Since
then I have not seen one. There was a second paper
published from the vets at the U of Georgia also
describing vaccine site sarcomas in pet ferrets.
Ferrets can also get fibrosarcomas that have nothing
to do with a vaccine or injection.
In cats there has been a lot of research on this very topic.
Some cats are genetically prone to sarcomas after an injection
(vaccines and several other products) produces inflammation
under the skin. The inflammation eventually leads to tumor formation.
Researchers at Colorado State's vet school also produced a sarcoma
with just the needle going thru the cat's skin without an injection.
The needle brought a small amount of hair under the skin which
caused the inflammation. This same problem has also been
documented in some lab animals (rodents).
Unfortunately there is no way of knowing for sure if his tumor
was produced by previous injections (ie vaccines, antibiotics,
SQ fluids, melatonin implant) or if it was a fibrosarcoma that had
nothing to do with an injection without a lot of specific testing.
Again sorry to hear about your loss,
Jerry Murray, DVM
END QUOTE
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