Message Number: FHL10099 | New FHL Archives Search
From: Sukie Crandall
Date: 2009-10-20 16:06:35 UTC
Subject: Re: [ferrethealth] wound care
To: fhl <ferrethealth@yahoogroups.com>

I would not unless you treating vet says to go ahead.

If the vet says to go ahead DO know that tea tree oil and lavender oil=20
each have been shown to be highly estrogenic in mammals, so they have=20
the potential to cause the same symptoms (and perhaps complications)=20
as adrenal disease can cause.

Here's a reference:
http://ferrethealth.org/archive/SG17746

For Science News subscribers:
<http://www.sciencenews.org/view/generic/id/7506/title/Lavender_Revolution_=
Plant_essences_linked_to_enlarged_breasts_in_boys
>

and

http://www.ncbi.nlm.nih.gov/pubmed/17267908

with full text here:

http://content.nejm.org/cgi/content/full/356/5/479

BEGIN QUOTED ABSTRACT
N Engl J Med. 2007 Feb 1;356(5):479-85
Prepubertal gynecomastia linked to lavender and tea tree oils.
Henley DV, Lipson N, Korach KS, Bloch CA.
Receptor Biology Section, Laboratory of Reproductive and Developmental=20
Toxicology, National Institute of Environmental Health Sciences,=20
Research Triangle Park, NC 27709, USA.

Most cases of male prepubertal gynecomastia are classified as=20
idiopathic. We investigated possible causes of gynecomastia in three=20
prepubertal boys who were otherwise healthy and had normal serum=20
concentrations of endogenous steroids. In all three boys, gynecomastia=20
coincided with the topical application of products that contained=20
lavender and tea tree oils. Gynecomastia resolved in each patient=20
shortly after the use of products containing these oils was=20
discontinued. Furthermore, studies in human cell lines indicated that=20
the two oils had estrogenic and antiandrogenic activities. We conclude=20
that repeated topical exposure to lavender and tea tree oils probably=20
caused prepubertal gynecomastia in these boys. 2007 Massachusetts=20
Medical Society

PMID: 17267908


END QUOTE

A later independent study confirmed estrogenic potential but not which
components are to blame:

http://www.ncbi.nlm.nih.gov/pubmed/18255254

BEGIN QUOTE

Toxicol In Vitro. 2008 Jun;22(4):1038-42. Epub 2007 Dec 31. Links
What you see may not always be what you get--bioavailability and=20
extrapolation from in vitro tests.
Nielsen JB.
Environmental Medicine, Institute of Public Health, University of=20
Southern Denmark, Winsl=F8wparken 17, DK-5000 Odense C, Denmark. jbnielsen@=
health.sdu.dk
<jbnielsen@health.sdu.dk>

In human risk assessment, bioavailability needs to be considered when=20
relying on in vitro toxicity results. For single chemicals, this=20
quantitative challenge is often handled through a bioavailability=20
factor. For mixtures, however, things are more complicated. Thus,=20
individual constituents may not only interact toxicodynamically and=20
toxicokinetically, but the composition of constituents reaching the=20
target site may also differ from what was present at the site of=20
exposure due to the differences in their bioavailabilities. A recent=20
study concluded on the in vivo potential of Australian tea-tree oil=20
(TTO) to act as an endocrine disruptor based on an in vitro protocol=20
measuring the growth of MCF-7 cells following chemical exposure to=20
TTO. TTO is primarily used topically in humans, and is not a single=20
chemical but is a mixture with some constituents penetrating the skin=20
which others do not. The present study evaluated in an identical in=20
vitro model to what extent TTO and its skin penetrating constituents=20
affected the growth of MCF-7 cells. The estrogenic potency of TTO was=20
confirmed, but none of the bioavailable TTO constituents demonstrated=20
estrogenicity. The present study, therefore, cautions in vitro to in=20
vivo extrapolations from the mixtures of constituents with potentially=20
varying bioavailabilities.

PMID: 18255254

END QUOTE


On Oct 20, 2009, at 10:37 AM, laferret55 wrote:

>
> I have a older ferret with a growth on her back. Been to the vets=20
> and got antibotic. I have Derma Dream Natural Healing Salve, for dog=20
> cats and other friends. Ingreadents vegetable oil soy and almound=20
> and caster oil coconut oil avocado oil bees wax squalene camuba=20
> [palm] wax vitiamin a vitiam d and e marigold aloe tea tree oil myth=20
> gum oil and lavander oil .
>
> Can I use this on her wound to clean it between visites?
>

Sukie (not a vet)

Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html

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