From:
Sukie Crandall
Date: 2009-11-17 04:40:04 UTC
Subject: [ferrethealth] KIT-positive tumor in ferret
To: fhl <ferrethealth@yahoogroups.com>, fg <ferret-genetics@yahoogroups.com>
(Bccing to some vets)
As Dr. Michelle Hawkins has expressed in the past, sometimes things=20
just stink of genetics. If I understand this properly this is just=20
such a situation:
http://www.ncbi.nlm.nih.gov/pubmed/19901303
> J Vet Diagn Invest. 2009 Nov;21(6):915-7.
> A KIT-positive gastrointestinal stromal tumor in a ferret (Mustela=20
> putorius furo).
> Girard-Luc A, Prata D, Huet H, Lagadic M, Bernex F.
> Unit=E9 d'Embryologie, d'Histologie et d'Anatomie Pathologique and=20
> INRA UMR 955, Ecole Nationale V=E9t=E9rinaire d'Alfort, 7 avenue du=20
> G=E9n=E9ral de Gaulle, 94704 Maisons-Alfort Cedex, France.
> A 1.5-year-old, neutered, male ferret (Mustela putorius furo) was=20
> presented with sudden lethargy, anorexia, and diarrhea. Clinical and=20
> radiographic examinations revealed an intra-abdominal mass. An=20
> explorative laparotomy was performed. A neoplasm, located in the=20
> ileum wall, was submitted for histopathologic examination. The tumor=20
> consisted of weakly eosinophilic spindle cells arranged in a compact=20
> pattern with haphazardly interlacing bundles. Neoplastic cells=20
> labeled positively for KIT (cluster of differentiation 117, stem=20
> cell factor receptor) and vimentin. Based on histologic and=20
> immunohistologic results, this tumor was diagnosed as a=20
> gastrointestinal stromal tumor. Results suggest that this ferret=20
> tumor shares strong similarities with the canine and human=20
> counterparts.
> PMID: 19901303 [PubMed - in process]
Some other abstracts on ferrets and relatives:
retinal: http://www.ncbi.nlm.nih.gov/pubmed/19790267
Wild relatives and their viruses in France:
http://www.ncbi.nlm.nih.gov/pubmed/18957635
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
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