Date: 2009-12-01 03:36:14 UTC
Subject: Re: [ferrethealth] Re: Heartworms?
Beware of overinterpretation of this document. It mentions one
instance of toxicity. The table legend includes the following: "IN
ALL INSTANCES, DOSE WAS NOT QUANTIFIED. THE SIZE OF THE EXPOSURE
CANNOT BE DETERMINED WITH ACCURACY IN MOST CASES." (All caps is due
to copy/paste from the document) In other words, there is no way to
know that this was not a massive overdose.
In this reference, ivermectin was "Used as anthel-mintic", but no
information on how it was used is given. Was it topical? Oral?
Injection? Was it mixed/ diluted with anything.
Footnotes to the table say: "1. Number of animals per case ranged
from 1 to 22,000." and "Clinical signs in some cases are as
described by the animal owner to NAPCC toxicologists, and in other
cases as described by the referring veterinarian. The quality of this
type of data is therefore somewhat variable".
In other words, this is a random data bit with no background and no
supporting information so any interpretation is purely conjecture.
In a quick (but not exhaustive) literature search, I find no other
instances of ferret death caused by administration of ivermectin.
Instead, I find references by respected ferret vets (e.g., Dr. Heidi
Hoefer and Dr. Sonia Hernandez-Divers as well as Dr. Cottrell)
recommending ivermectin for safe heartworm prophylaxis in ferrets.
Please educate me if there are other known cases of ivermectin toxicity.
Sorry if all of this sounds a bit strident, but this document keeps
being used as a significant reference and it really does not seem
like one to me.
Thanks for your patience.
On Nov 30, 2009, at 5:22 PM, ytonytcla wrote:
> I should be wary of ivermectin it can be fatal to ferrets.
[Non-text portions of this message have been removed]
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