From:
Sukie Crandall
Date: 2009-01-14 22:24:55 UTC
Subject: [ferrethealth] abstract (ferrets are an often used model animal for albino eyes)
To: fhl <ferrethealth@yahoogroups.com>
http://www.ncbi.nlm.nih.gov/pubmed/19139858
BEGIN QUOTED ABSTRACTS
Exp Brain Res. 2009 Jan 13. [Epub ahead of print]
Retinal projections to the accessory optic system in pigmented and=20
albino ferrets (Mustela putorius furo).
Distler C, Korbmacher H, Hoffmann KP.
Allgemeine Zoologie and Neurobiologie, Ruhr-Universit=E4t Bochum,=20
Postfach 102148, 44780, Bochum, Germany
We investigated if a reduced specificity of the retinal projection to=20
the accessory optic system might be responsible for the loss of=20
direction selectivity in the nucleus of the optic tract and dorsal=20
terminal nucleus (NOT-DTN) and, in consequence of this, the=20
optokinetic deficits in albino ferrets. Under electrophysiological=20
control we performed dual tracer injections into the NOT-DTN and the=20
medial terminal nucleus (MTN). Retrogradely labelled ganglion cells=20
were found in the visual streak, the dorsal, and the ventral retina=20
both after injections into the NOT-DTN and the MTN indicating that=20
both nuclei receive input from the same retinal regions. The=20
distribution and spacing of labelled ganglion cells did not differ=20
between pigmented and albino ferrets. However, retinal ganglion cells=20
projecting simultaneously to both the NOT-DTN and the MTN occurred=20
only in albino ferrets. These results suggest that a reduced=20
specificity of the projection pattern of direction specific ganglion=20
cells may contribute to the loss of direction selectivity in the NOT-
DTN in albino ferrets.
PMID: 19139858
END QUOTE
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Non-text portions of this message have been removed]
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