From:
AFERRETVET@cs.com
Date: 2009-02-05 02:39:47 UTC
Subject: [ferrethealth] Re: Lupron dose
To: ferrethealth@yahoogroups.com
Hi Amanda, Karen, and Katherine
When people are talking about what dose of Lupron
to use for adrenal gland disease:
one thing to consider is the adrenal gland itself.
Typically the diseased adrenal gland(s) is classified as
either hyperplasia (pre cancer), adenoma (benign cancer),
or carcinoma (malignant cancer). One can expect cases of
hyperplasia and adenomas to respond much better to Lupron
than cases of carcinomas. Likewise if the adrenal cancer has spread
to the liver, spleen, or to other areas in the abdomen, then Lupron
may not control the clinical signs that well.
The normal dose of Lupron is 100 to 500 mcg per month. Roughly
80% respond well to the 100 mcg dose, roughly another 10%
will respond to the higher dose range (200 to 500 mcg), but ~10%
do not respond to Lupron. Those "nonresponders" are usually
carcinomas. That has been my experience with Lupron over the past
11 years down here in the South.
Hope that helps,
Jerry Murray, DVM
Dallas, Texas
[Non-text portions of this message have been removed]
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