From: "Karen McCabe"
Date: 2009-04-03 20:59:45 UTC
Subject: [ferrethealth] Re: Okay this is weird
Chances are, the TN panel did not detect the problem because lupron was being given. Lupron controls the hormone levels the panel tests for. With lupron lowering these hormones the panel would not detect it.
[Lupron was NOT being given at the time of any of the TN Panel tests,
nor was melatonin, so, no, that explanation does not work in this case,
and would have been considered if it had been. --SDC]
My concern would be malignancy. This would explain why Whizbang did not respond well to the lupron. If the lab made an error, and it does sound as if they did, malignancy can not be confirmed or ruled out. I would assume it though based on what you've been seeing.
I would also be concerned about the nodes. This could indicate lymphoma, even though the nodes have remained the same size for some time. However, it's also possible the diseased adrenal gland caused them to enlarge. Again, proper biopsy would have given you an answer.
[That they could not be removed is a concern, but they are stable. --SDC]
In my opinion, based on my experiences, I would say that what you're seeing is very common and ordinary, rather then something rare.
[No, everything common has already been discounted, not only by the
treating vets but by consultants. Whichever form of growth it is it does
not produce the normal responses nor the normal test results. There
are several types of possible growths, but all the ones mentioned by the
experts are rare or a rare variation on a more typical type of growth. --SDC]
Without biopsy, I would assume malignancy, rather then anything odd or extraordinary, and treat accordingly.
[Without biopsy the clinical observations at removal are actually more
similar to benign possibilities, but we should know either tomorrow or
Monday if the mislabeling just happened to papers or to tissue and then
tests can be redone if only to the papers. --SDC]
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