From: "Karen McCabe"
Date: 2009-04-29 20:28:38 UTC
Subject: [ferrethealth] Re: What should I do?
--- In email@example.com, "Karen McCabe" <cinnamon_sprite@...> wrote:
> [Moderator's request:
> Fat does produce estrogen, but does it act in response to
> LH or FSH, or are you just saying that perhaps it might?
> Supportive studies, please?]
Perhaps my wording was not appropriate (sometimes, ok often times, I understand better then I explain....I would be a lousy teacher! lol). It is not the fat the causes the problem but rather accessory adrenal tissue that can be located in the fat.
If subtotal or total bilateral adrenalectomy is performed, longterm post-operative treatment with glucocorticoids is often necessary. The dosage it titrated to the individual patient and tapered to the lowest dosage interval necessary to prevent clinical signs of hypoadrenocorticism. Many ferrets have accessory adrenal tissue, and some may be weaned from exogenous steroids completely if carefully monitored.
In one study, an accessory adrenal gland was found in 38% of the ferrets . This accessory tissue explained why electrolytes levels were within reference range after a total bilateral adrenalectomy, as in the case described above.
Both adrenal glands were surgically removed. The histopathological diagnosis of both glands was adrenocortical adenoma. The animal received glucocorticoid treatment for one week following surgery. Several examinations revealed that the hair had grown, and electrolyte levels were checked to rule out an hypoadrenocorticism. Sodium and potassium levels were within normal values. These results suggested this ferret had some accessory adrenal tissue, although it could not be identified by ultrasonography.
Accessory adrenal tissue was found in 11 of 135 animals examined. In light of the anatomic arrangement of the adrenal glands, a total adrenalectomy of the ferret is difficult.
Accessory adrenal tissue may be present in the adjacent tissues.
accessory adrenal tissue has only been described close to an adrenal gland or in the cranial perirenal fat of ferrets.
Accessory adrenal tissue was not identified during the sonographic examination but was grossly found in 10 of the ferrets. It was associated with either the right, left or both adrenal glands.
Accessory adrenal tissue may be present in some ferrets.
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