From:
Sukie Crandall
Date: 2009-05-06 04:00:27 UTC
Subject: [ferrethealth] Abstract
To: fhl <ferrethealth@yahoogroups.com>
BEGIN QUOTED ABSTRACT
Am J Vet Res. 2009 May;70(5):619-23.
Assessment of cytologic evaluation of preputial epithelial cells as a
diagnostic test for detection of adrenocortical disease in castrated
ferrets.
Protain HJ, Kutzler MA, Valentine BA.
Department of Clinical Sciences, College of Veterinary Medicine,
Oregon State University, Corvallis, OR 97331.
Objective-To determine whether results of cytologic evaluation of
preputial epithelial cells correspond to results of a serum endocrine
hormone assay and clinical signs associated with adrenocortical
disease in castrated ferrets. Animals-13 clinically normal ferrets and
8 ferrets with signs of adrenocortical disease. Procedures-Blood and
preputial lavage samples were collected from each ferret. Serum
samples were submitted to the University of Tennessee Veterinary
Diagnostic Laboratory for performance of an endocrine hormone assay.
Differential epithelial cell counts were performed on preputial lavage
samples to determine the percentage of cornified cells. Results of
cytologic evaluation were compared with results of the endocrine
hormone assay and clinical status of ferrets. Results-The percentage
of cornified preputial epithelial cells was not significantly
correlated with serum 17B-estradiol or androstenedione concentration
but was significantly correlated with serum 17-hydroxyprogesterone
concentration (r = 0.60). The percentage of cornified preputial
epithelial cells was higher in ferrets with clinical signs of
adrenocortical disease (mean +/- SD, 71.3 +/- 16.9%) than in
clinically normal ferrets (55.5 +/- 19.0%). Conclusions and Clinical
Relevance-Cornification of preputial epithelial cells was correlated
with an increase in serum 17-hydroxyprogesterone concentration as well
as clinical signs of adrenocortical disease in castrated ferrets.
Additional investigation is needed to elucidate the mechanism of
preputial epithelial cell cornification in castrated ferrets.
PMID: 19405901
END QUOTE
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Non-text portions of this message have been removed]
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