Message Number: FHL9603 | New FHL Archives Search
From: Sukie Crandall
Date: 2009-08-02 15:59:12 UTC
Subject: [ferrethealth] abstracts, canine distemper (another thing affecting titers), Aleutian Disease
To: Ferret Mailing List <ferret-l@LISTSERV.FERRETMAILINGLIST.ORG>, fhl <>

Opps, somehow I accidently left off an abstract about one of the
studies on things that can affect titer levels. I was trimming from
some resources I found for someone in the past and trimmed a bit too

> Vet Ther. 2005 Spring;6(1):43-56.Links
> The role of supplementary dietary antioxidants on immune response in
> puppies.
> Khoo C, Cunnick J, Friesen K, Gross KL, Wedekind K, Jewell DE.
> Hill's Pet Nutrition Inc, PO Box 1658, Topeka, KS 66601-1658, USA.
> The objective of this study was to evaluate the effect of
> supplementary antioxidants (AOX) and whey protein on the immune
> function health of puppies. Four groups of 10 puppies were fed a
> control and 3 different test foods (control + antioxidants (AOX),
> control + AOX + 1% whey protein, and a grocery brand (low AOX)) for
> 6 weeks. A standard vaccination protocol with a combination canine
> parvovirus (CPV) and distemper (CDV) vaccine was carried out at 2
> and 4 weeks. The results showed that animals on high AOX foods had
> significantly increased titers, memory cells and serum E
> concentrations compared to the control and groc groups respectively.
> PMID: 15906269

BTW, this is old but i just ran across it for what I think is the
first time so it might help some ferrets:

> J Pineal Res. 1996 Nov;21(4):214-7.Links
> Melatonin reduces mortality from Aleutian disease in mink (Mustela
> vison).
> Ellis LC.
> Department of Biology, Utah State University, Logan 84322-5305, USA.
> Aleutian disease (AD) results from a persistent parvoviral infection
> that results in marked hypergammaglobulinemia and immune complex
> mediated lesions of the kidney, liver, lungs and, arteries.
> Melatonin protected both a wild type or demi strain and a demi/dark
> crossed strain of mink from AD. The biogenic amine also afforded
> protection against other non-diagnosed diseases naturally found on
> mink farms when it was available from a subcutaneously-placed
> reservoir. Some genetic strains of mink apparently differed in the
> resistance of mink to the virus and in the protective ability of
> melatonin. The demi strain was the most resistant followed by
> pastels, mahogany, darks, and those strains with the double
> recessive Aleutian gene. The protective action of melatonin appeared
> to result from melatonin's ability to scavenge free radicals, but it
> could also be due to the induction of antioxidant enzymes or to the
> modulation of immunity. Melatonin also protected mink against
> distemper.
> PMID: 8989719

Sukie (not a vet)

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