From:
Sukie Crandall
Date: 2010-01-22 18:48:17 UTC
Subject: [ferrethealth] abstract: a CDV variant (Bavaria)
To: fhl <ferrethealth@yahoogroups.com>
as opposed to a variant two years earlier in two ferrets:
> Vet J. 2010 Jan 19. [Epub ahead of print]
> Emergence of canine distemper in Bavarian wildlife associated with a=20
> specific amino acid exchange in the haemagglutinin protein.
> Sekulin K, Hafner-Marx A, Kolodziejek J, Janik D, Schmidt P, Nowotny=20
> N.
> Zoonoses and Emerging Infections Group, Clinical Virology,=20
> Department of Pathobiology, University of Veterinary Medicine,=20
> Vienna, Veterin=E4rplatz 1, 1210 Vienna, Austria.
> A widespread, severe outbreak of canine distemper encephalitis was=20
> observed in wildlife in Southern Bavaria in the spring and summer of=20
> 2008. The haemagglutinin (HA) genes of six representative canine=20
> distemper virus (CDV) samples originating from five red foxes and=20
> one badger during this outbreak had a Y549H amino acid substitution=20
> in the HA protein compared to sequences from two captive=20
> domesticated ferrets which succumbed to CDV in the same area 2years=20
> earlier. As this specific substitution at the receptor-binding site=20
> has been hypothesised to contribute to the emergence of CDV and its=20
> spread to novel hosts, the outbreak in wildlife in Southern Bavaria=20
> might, directly or indirectly, be associated with a Y549H amino acid=20
> exchange. Copyright =A9 2009 Elsevier Ltd. All rights reserved.
> PMID: 20089424
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
HAPPY: http://www.6footsix.com/my_weblog/2010/01/high-fives-for-happiness.=
html
"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)
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