From:
Sukie Crandall
Date: 2010-01-28 04:46:00 UTC
Subject: [ferrethealth] abstracts
To: fhl <ferrethealth@yahoogroups.com>
2 testicular neoplasums in a ferret:
http://www.ncbi.nlm.nih.gov/pubmed/20088849
and
http://www3.interscience.wiley.com/journal/123243984/abstract?CRETRY=3D1&SR=
ETRY=3D0
> Testicular Neoplasms (Interstitial and Sertoli Cell Tumours) in a=20
> Domestic Ferret (Mustela putorius furo)
> M Batista-Arteaga 1 , A Su=E1rez-Bonnet 2 , M Santana 1 , T Ni=F1o 1 , R =
> Reyes 1 and D Alamo 1
> 1 Unit of Reproduction and Obstetrics, Veterinary Faculty,=20
> University of Las Palmas de Gran Canaria, Las Palmas, Spain ; 2 Unit=20
> of Comparative Pathology, Veterinary Faculty, University of Las=20
> Palmas de Gran Canaria, Las Palmas, Spain
> Author's address (for correspondence): Miguel Batista-Arteaga, Unit=20
> of Reproduction and Obstetrics, Veterinary Faculty, University of=20
> Las Palmas de Gran Canaria, Las Palmas, Spain.
> ABSTRACT
> Unilateral testicular enlargement was detected in a 5-years-old=20
> domestic ferret during a routine sterilization. The right testicle=20
> showed two different types of proliferative lesions: (i) round=20
> nodules, well demarcated, showing a soft yellow tissue; (ii) white=20
> nodules, firm, with irregular-shaped invaginations. Microscopically,=20
> the neoplastic proliferations were identified as an interstitial=20
> neoplasm and Sertoli cell tumour, respectively. The left testicle=20
> was small and showed intense testicular atrophy. Clinical evaluation=20
> of the ferret did not show any other apparent pathological=20
> processes. This study is the first case reporting the concomitant=20
> occurrence of a Sertoli cells tumour and an interstitial cell tumour=20
> in a domestic ferret.
>
Petrochemical related adrenal hypertrophy in mink:
http://www.ncbi.nlm.nih.gov/pubmed/20090023
Mineral oil was used for the comparison groups and the rest got things=20
like weathered fuel oil.
and
http://www.jwildlifedis.org/cgi/content/full/46/1/103
> Journal of Wildlife Diseases, 46(1), 2010, pp. 103-110
> =A9 Wildlife Disease Association 2010
> FUEL OIL=96INDUCED ADRENAL HYPERTROPHY IN RANCH MINK (MUSTELA VISON): =
> EFFECTS OF SEX, FUEL OIL WEATHERING, AND RESPONSE TO=20
> ADRENOCORTICOTROPIC HORMONEF. C. Mohr1,4, B. Lasley2 and S. Bursian3
> 1 Department of Veterinary Pathology, Microbiology and Immunology,=20
> School of Veterinary Medicine, University of California, Davis,=20
> California 95616, USA
> 2 Department of Population Health and Reproduction, School of=20
> Veterinary Medicine, University of California, Davis, California=20
> 95616, USA
> 3 Department of Animal Science, Michigan State University, East=20
> Lansing, Michigan 48824, USA
>
>
> ABSTRACT: Environmental contamination by petroleum hydrocarbons=20
> from anthropogenic sources can be a cause of stress for free-ranging=20
> wildlife. The response of wildlife to chemical contaminants requires=20
> that the hypothalamic=96pituitary=96adrenal (HPA) axis be precisely=20
> regulated to allow for proper glucocorticoid-mediated adaptive=20
> responses. Chronic oral exposure to low concentrations of bunker C=20
> fuel oil causes the development of adrenal hypertrophy in male ranch=20
> mink (Mustela vison) without increasing serum or fecal=20
> glucocorticoid concentrations. This hypertrophy is an adaptive=20
> response to fuel oil-induced adrenal insufficiency. To determine if=20
> the same phenomenon occurs in female mink or male mink exposed to=20
> artificially weathered fuel oil, female mink were fed 0 ppm (mineral=20
> oil) or 420 ppm fuel oil and male mink were exposed to 0 ppm, 420=20
> ppm fuel oil, or 480 ppm artificially weathered fuel oil in the diet=20
> for 60=9662 days. At the end of the exposure, serum glucocorticoid=20
> concentrations were assayed along with body and organ weight=20
> measurements. Fecal glucocorticoid concentrations were assayed at=20
> time points throughout the exposure. Male mink fed fuel oil or=20
> weathered fuel oil and female mink fed fuel oil had adrenal=20
> enlargement without any significant increases in the serum or fecal=20
> concentration of glucocorticoids, which is consistent with fuel oil=96
> induced adrenal insufficiency. To address the physiological=20
> consequences of adrenal insufficiency, fuel oil=96exposed male mink=20
> were administered an adrenocorticotropic hormone (ACTH)=20
> stimulationtest. Fuel oil=96exposed animals had a smaller incremental =
> increase in serum glucocorticoid concentration after ACTH challenge=20
> compared to control animals. Our findings provide further evidence=20
> that the HPA axis of fuel oil=96exposed animals is compromised and,=20
> therefore, not able to respond appropriately to the diverse=20
> stressors found in the environment.
> Key words: Adrenal insufficiency, bunker C fuel oil,=20
> glucocorticoid, Mustela vison, petroleum oil, ranch mink, stress=20
> response.
>
>
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
HAPPY: http://www.6footsix.com/my_weblog/2010/01/high-fives-for-happiness.=
html
"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)
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