Message Number: FHL10918 | New FHL Archives Search
From: Andrea
Date: 2010-02-07 21:15:44 UTC
Subject: Re: [ferrethealth] Proglycem Dosing question
To: ferrethealth@yahoogroups.com

I think I know what your vet was referring to with the "chemo" dose of Pred=
... Although I'm not sure that there is a set min or max dosage amount for =
it, but I think basically what he means is that if your ferret is on Pred f=
or insulinoma, and then after that develops lymphoma or something, that the=
lymphoma will be considered chemo resistant because of him already being o=
n the Pred.=A0 The Pred interferes with the chemo drugs - this is according=
to my vet who is a top-notch vet very experienced in dealing w/ chemo drug=
s.=A0

Proglycem (diazoxide) is pretty expensive.=A0 There are some online compoun=
ding pharms that you can order from that may be cheaper than others.=A0 The=
y are in the files section of this group.=A0 The benefit to Proglycem inste=
ad of Pred is that Kyle wont get the side effects of the Pred (pred belly..=
etc).=A0

As you are now adding on the Proglycem (and also the fact that Kyle had a l=
ow BG reading), your vet is playing with the dosing amounts to try to figur=
e out the right dosages of both meds.=A0 If you dont feel comfortable reduc=
ing the Pred that quickly, talk to the vet about it, and they could recomme=
nd a different dosage.=A0 Same with the proglycem dosage, if you think its =
too high (but also remember that 50 was low on the Pred amount, so technica=
lly if you werent adding in the proglycem you would be raising the Pred), d=
ouble check with the vet.=A0 BUT you just want to monitor him very closely =
to be sure his glucose wont drop too low if you do change the dosages aroun=
d.=A0 I would definately double check all dosing amounts with your vet thou=
gh and go by what they recommend.=A0 I've dealt with insulinoma and pred an=
d proglycem a number of times now (unfortunately), and those dosages sound =
right to me.=A0
Andrea

--- On Sun, 2/7/10, jenferretgirl <jpaukstis@msn.com> wrote:
Hi.=A0 My ferret, Kyle is on pred - 5mg/ml and takes .15cc twice daily for =
insulinoma.=A0 His last sugar was 50.=A0 Initially, the vet told me, we wil=
l leave his pred dose as is - we couldn't go up on the pred bc if we did he=
would be "on a chemotherapy dose"(?).=A0 That's when I suggested Proglycem=
.=A0 I guess this vet's office may not use it that often, and I was dealing=
with one of the newer vets.=A0 She wasn't too sure about this suggestion, =
went off and consulted with (I'm assuming) the senior vet, and came out wit=
h a script for Proglycem.=A0 Ordered the 50mg/ml and told me to start him o=
n .2cc twice daily and immediately decrease pred dose to .1 twice daily.=A0=
I talked to a friend who has a ferret on Proglycem and she has me question=
ing the vet's recommendations.=A0 Does the proglycem dose sound too high? S=
hould he maybe start with .1cc of Proglycem twice daily (He weighs 1.01kg) =
Should I be decreasing the pred more gradually???=A0 I will call the vet on
Monday to discuss further, but I'm just wondering what others who have had=
experience think about this.=A0 Thanks!!!!




=20=20=20=20=20

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