From:
"Julie"
Date: 2010-05-14 01:49:14 UTC
Subject: [ferrethealth] Re: URGENT: Extreme pain after 5 days post-op
To: ferrethealth@yahoogroups.com
Pathology Report came back and since my vet was in a rush he basically
told me there was no cancer to worry about, there is something wrong
with her liver and that's why her BG was 320. He said it was most likely
caused by her "soft diet" (duck soup) and should get better on it's own.
Now I really am frustrated. I was hoping this would give me some answers
to why she is so sick.
Can someone translate this to me in laymans terms-
"The other significant change is that associated with the liver. These
changes are suggested of an endocrine disruption affecting metabolism of
lipids and carbohydrates. These changes in the liver are reversable
however the inciting cause is not determined."
Thank you so much!
Pathology Report
Examined are multiple tissues from a 7-year-old, female spayed ferret.
Slide A. Liver: The hepatocytes are slightly to moderately enlarged with
an eosinophilic to clear lacy cytoplasm consistent with collagen
deposition or hydropic change. There are scattered foci of vacuolar
change in which vacuoles are sharply demarcated consistent with lipid
and indicative of clear-cell foci. The serosal surface of the liver
section examined is serrated which would be consistent with diffuse
hepatocellular swelling.
Pancreas: Within the Pancreas is a single nodular focus of exocrine
pancreatic nodular hyperplasia. Within this focus pancreatic acinar
cells contain more abundant zymogen granules.
Slide B. Spleen: The spleen is diffusely markedly congested with
multifocal differential congestion with formation of nodular foci. There
is diffuse moderate to marked extramedullary hematopoiesis with all
cellular lineages represented.
COMMENTS:
There are 2 significant histopathologic changes. There is marked,
splenic extramedullary hematopoiesis. Is not uncommon for an aged animal
to have extramedullary hematopolesis. In some cases it can be associated
with disease or displacement from bone marrow cavities. There is no
indication of the latter in this case. The other significant change is
that associated with the liver. These changes are suggested of an
endocrine disruption affecting metabolism of lipids and carbohydrates.
These changes in the liver are reversable however the inciting cause is
not determined.
DIAGNOSES:
Moderate, diffuse, hepatocellular hydropic change; liver.
Minimal, multifocal, clear-cell foci (hepatic lipidosis); liver
Marked, diffuse, splenic congestion.
Marked, diffuse, splenic extramedullary hematopoiesis.
Minimal, focal pancreatic nodular hyperplasis
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