Message Number: FHL11692 | New FHL Archives Search
From: Sukie Crandall
Date: 2010-06-18 20:25:06 UTC
Subject: [ferrethealth] abstract
To: fhl <>


> 1. Open Dent J. 2010 Apr 29;4:37-47. Experimental animal models in
> periodontology: a review. Struillou X, Boutigny H, Soueidan A,
> Layrolle P. Department of Periodontology, Faculty of Dental Surgery,
> University of Nantes, 1 Place Alexis Ricordeau, 44042 Nantes,
> France. In periodontal research, animal studies are complementary to
> in vitro experiments prior to testing new treatments. Animal models
> should make possible the validation of hypotheses and prove the
> safety and efficacy of new regenerating approaches using
> biomaterials, growth factors or stem cells. A review of the
> literature was carried out by using electronic databases (PubMed,
> ISI Web of Science). Numerous animal models in different species
> such as rats, hamsters, rabbits, ferrets, canines and primates have
> been used for modeling human periodontal diseases and treatments.
> However, both the anatomy and physiopathology of animals are
> different from those of humans, making difficult the evaluation of
> new therapies. Experimental models have been developed in order to
> reproduce major periodontal diseases (gingivitis, periodontitis),
> their pathogenesis and to investigate new surgical techniques. The
> aim of this review is to define the most pertinent animal models for
> periodontal research depending on the hypothesis and expected
> results. PMID: 20556202 [PubMed - in process]

Sukie (not a vet)

Recommended ferret health links:
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"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)


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