From:
Sukie Crandall
Date: 2010-07-15 13:21:48 UTC
Subject: Re: [ferrethealth] Re: Ketofen
To: ferrethealth@yahoogroups.com
On Jul 15, 2010, at 5:54 AM, Tressie wrote:
> This medication (Ketofen) DOES contain Ibuprofen???
>
NOTE THAT MOST REFERENCES TO THIS DRUG ARE NOT IN FERRETS.
See the moderator's comments yesterday for ferret-specific links.
I don't see any indication that Ibuprofen is in there:
http://www.drugs.com/vet/ketofen.html
says:
> Ketoprofen is a non-steroidal anti-inflammatory agent of the=20
> propionic acid class that includes ibuprofen, naproxen and=20
> fenoprofen. Each mL of KETOFEN (ketoprofen) contains 100 mg of=20
> ketoprofen in an aqueous formulation containing: L-Arginine, 70 mg;=20
> citric acid (to adjust pH); benzyl alcohol, 0.025 g (as preservative)
http://www.petplace.com/drug-library/ketoprofen-ketofen/page1.aspx
includes:
> =95 Precautions and Side Effects
>
> =95 While generally safe and effective when prescribed by a=20
> veterinarian, ketoprofen can cause side effects in some animals.
> =95 Ketoprofen should not be used in animals with known=20
> hypersensitivity or allergy to the drug.
> =95 Ketoprofen should be avoided in animals with liver, heart or=20
> blood abnormalities.
> =95 Ketoprofen should also be avoided in animals with=20
> gastrointestinal disorders, including ulcers.
> =95 Ketoprofen may interact with other medications. Consult with your =
> veterinarian to determine if other drugs your pet is receiving could=20
> interact with ketoprofen. Such drugs include aspirin, other NSAIDs,=20
> corticosteroids and heparin.
> =95 The most common adverse effects associated with ketoprofen are=20
> vomiting, diarrhea, lethargy and lack of appetite.
> =95 Stomach ulcers and kidney impairment are possible.
This includes things like side effects in cats:
http://www.ehow.com/facts_5539436_side-effects-ketofen-elixir-cats.html
Chemical structure and diagram in
http://www.newdruginfo.com/pharmacopeia/usp28/v28230/usp28nf23s0_m44002.htm
includes
> C16H14O3 254.28
>
> Benzeneacetic acid,3-benzoyl-a-methyl-,(=B1)-.
> (=B1)-m-Benzoylhydratropic acid [22071-15-4].
> =BBKetoprofen contains not less than 98.5percent and not more than=20
> 101.0percent of C16H14O3,calculated on the dried basis.
while the diagram and chemical formula for ibuprofen can be found here:
http://www.rxlist.com/combunox-drug.htm
which includes
> Ibuprofen is a nonsteroidal anti-inflammatory drug with analgesic=20
> and antipyreticproperties. Its chemical name is (=B1)-2-(p-
> isobutylphenyl) propionic acid. Its chemical formula is C13H18O2 and=20
> molecular weight is 206.29. Its structural formula is:
so
C16H14O3 for the Ketprofen
but a quite different
C13H18O2 for Ibuprofen
though, honestly, I must sadly and shamefully admit that I stink at=20
chemistry.
More:
http://www.medicinenet.com/ketoprofen/article.htm
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a686014.html
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
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