From:
"suedvm96"
Date: 2010-07-16 16:20:34 UTC
Subject: [ferrethealth] Re: Ketofen
To: ferrethealth@yahoogroups.com
This drug is in the same class as Ibuprofen it isn't ibuprofen. Just as Ca=
rprofen (aka Rimadyl) is in the same class, so that while some of the effec=
ts can be similar there have been some studies in animals. I personally do=
n't use it. With so many ferrets having insulinoma and recieving prednisol=
one I don't use many NSAID's since we can't use them both together. But th=
ere are times I use one I prefer Meloxicam (Metacam in the states).=20
Just figured I would add a little here.
Dr. Sue
TLC First Animal Hospital
Chicago, IL 60631
--- In ferrethealth@yahoogroups.com, Sukie Crandall <sukie@...> wrote:
>
>
> On Jul 15, 2010, at 5:54 AM, Tressie wrote:
>
> > This medication (Ketofen) DOES contain Ibuprofen???
> >
>
> NOTE THAT MOST REFERENCES TO THIS DRUG ARE NOT IN FERRETS.
> See the moderator's comments yesterday for ferret-specific links.
>
> I don't see any indication that Ibuprofen is in there:
>
> http://www.drugs.com/vet/ketofen.html
> says:
> > Ketoprofen is a non-steroidal anti-inflammatory agent of the=20
> > propionic acid class that includes ibuprofen, naproxen and=20
> > fenoprofen. Each mL of KETOFEN (ketoprofen) contains 100 mg of=20
> > ketoprofen in an aqueous formulation containing: L-Arginine, 70 mg; =
> > citric acid (to adjust pH); benzyl alcohol, 0.025 g (as preservative)
>
> http://www.petplace.com/drug-library/ketoprofen-ketofen/page1.aspx
> includes:
> > =95 Precautions and Side Effects
> >
> > =95 While generally safe and effective when prescribed by a=20
> > veterinarian, ketoprofen can cause side effects in some animals.
> > =95 Ketoprofen should not be used in animals with known=20
> > hypersensitivity or allergy to the drug.
> > =95 Ketoprofen should be avoided in animals with liver, heart or=20
> > blood abnormalities.
> > =95 Ketoprofen should also be avoided in animals with=20
> > gastrointestinal disorders, including ulcers.
> > =95 Ketoprofen may interact with other medications. Consult with your =
> > veterinarian to determine if other drugs your pet is receiving could =
> > interact with ketoprofen. Such drugs include aspirin, other NSAIDs, =
> > corticosteroids and heparin.
> > =95 The most common adverse effects associated with ketoprofen are =
> > vomiting, diarrhea, lethargy and lack of appetite.
> > =95 Stomach ulcers and kidney impairment are possible.
>
>
> This includes things like side effects in cats:
> http://www.ehow.com/facts_5539436_side-effects-ketofen-elixir-cats.html
> Chemical structure and diagram in
> http://www.newdruginfo.com/pharmacopeia/usp28/v28230/usp28nf23s0_m44002.h=
tm
> includes
> > C16H14O3 254.28
> >
> > Benzeneacetic acid,3-benzoyl-a-methyl-,(=B1)-.
> > (=B1)-m-Benzoylhydratropic acid [22071-15-4].
> > =BBKetoprofen contains not less than 98.5percent and not more than=20
> > 101.0percent of C16H14O3,calculated on the dried basis.
>
> while the diagram and chemical formula for ibuprofen can be found here:
> http://www.rxlist.com/combunox-drug.htm
> which includes
> > Ibuprofen is a nonsteroidal anti-inflammatory drug with analgesic=20
> > and antipyreticproperties. Its chemical name is (=B1)-2-(p-
> > isobutylphenyl) propionic acid. Its chemical formula is C13H18O2 and =
> > molecular weight is 206.29. Its structural formula is:
>
> so
> C16H14O3 for the Ketprofen
> but a quite different
> C13H18O2 for Ibuprofen
> though, honestly, I must sadly and shamefully admit that I stink at=20
> chemistry.
>
> More:
> http://www.medicinenet.com/ketoprofen/article.htm
> http://www.nlm.nih.gov/medlineplus/druginfo/meds/a686014.html
>
> Sukie (not a vet)
>
> Recommended ferret health links:
> http://pets.groups.yahoo.com/group/ferrethealth/
> http://ferrethealth.org/archive/
> http://www.afip.org/ferrets/index.html
> http://www.miamiferret.org/
> http://www.ferrethealth.msu.edu/
> http://www.ferretcongress.org/
> http://www.trifl.org/index.shtml
> http://homepage.mac.com/sukie/sukiesferretlinks.html
> all ferret topics:
> http://listserv.ferretmailinglist.org/archives/ferret-search.html
>
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