Message Number: FHL12235 | New FHL Archives Search
From: Sukie Crandall
Date: 2010-09-17 22:46:03 UTC
Subject: [ferrethealth] abstract
To: fhl <>

1. J Am Vet Med Assoc. 2010 Sep 15;237(6):695-700.
Immune-mediated pure red cell aplasia in a domestic ferret.
Malka S, Hawkins MG, Zabolotzky SM, Mitchell EB, Owens SD. William R.
Pritchard Veterinary Medical Teaching Hospital, School of Veterinary
Medicine, University of California-Davis, Davis, CA 95616.
Case Description-An 8-month-old spayed female domestic ferret
(Mustela putorius furo) was referred for examination to determine the
cause of lethargy and severe anemia. Clinical Findings-Initial
examination revealed that the ferret was lethargic but with
appropriate mentation. The only other abnormal findings were severe
pallor of the mucous membranes, nasal planum, and skin and a PCV of
8%. Pure red cell aplasia (PRCA) was diagnosed on the basis of
cytologic evaluation of a bone marrow biopsy specimen. Treatment and
Outcome-Medical treatment included blood transfusions, IM
administration of iron dextran, oral administration of antimicrobials
and gastrointestinal tract protectants, and SC administration of
erythropoietin. Once PRCA was diagnosed, the ferret was orally
administered prednisone, cyclosporine, and azathioprine. Nine months
after onset of treatment, the PRCA was in remission and the ferret was
doing well. Immunosuppressive treatment was discontinued at 14 months
after onset of treatment, and 36 months after initial examination, the
ferret appeared to be healthy. Clinical Relevance-It is important that
PRCA be considered as a differential diagnosis for a ferret with
severe anemia. Prolonged immunosuppressive treatment was successful in
the ferret described here. (J Am Vet Med Assoc 2010;237:695-700).
PMID: 20839993 [PubMed - in process]

Sukie (not a vet)

Recommended ferret health links:
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"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)


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