Message Number: FHL12728 | New FHL Archives Search
From: My Buddy
Date: 2011-01-08 16:36:14 UTC
Subject: [ferrethealth] Re: Again about Deslorelin a killing drug?

On 07 Jan 2011, at 21:05, ********* wrote:

> If it=E2=80=99s been 14 months, then it=E2=80=99s time for a new implant.=
You should probably not go beyond 12 months, and less than that if any fe=
rret has advanced adrenal disease.
So I=E2=80=99m a little confused now... because the official documents from=
Nico J. Schoemaker are only saying 18 a 24 months for the 4.7 mg. Suprelor=
I use it for chemical castration recommended by Hanneke Schoemaker... not f=
or adrenal disease!
So I go for the official proof like here (my wife was there)

7th EVSSAR Congress
May 14th-15th, 2010
Louvain-La-Neuve, Belgium


Symposium Deslorelin
Deslorelin in practice:

Maybe it was for the early deslorelin 1, 2 or 3 mg.? I don=E2=80=99t know!
Some forums etc. are speaking about replacing the implants every 6 or 12 mo=
nths for adrenal disease but use the same statement for chemical castration=
? Very confused.
But still nothing official...
My 2 hobs, nothing to feel or to see yet... no evidence of balls.
Do someone know how long it takes when (the balls) are coming back? Or when=
they are back activated?
My vet says it is still no time yet... and always speak about 20 a 24 month=
s... The same info after calling met Hanneke.

Regards and thank you.

[There are three uses for the Suprelorin implant
which releases deslorelin over time (and is not the
daily deslorelin).=20

Chemical castration appears to be the topic which
interests you, and your vet should be able to find
the current recommendation on that by contacting
Peptech Animal Health if the vet does not know it.
It might differ with the size of the implant.

It is also used on an annual basis for adrenal disease
prophylaxis with the smaller of the two implants.

The third use is for treatment of adrenal disease. Most
adrenal disease is mild and then repeating it annually
is sufficient. Currently, when the chances are that a
carcinoma is present it appears best to give the implant
every 6 months or perhaps try the larger implant. I do
not know how frequently the larger implant can be given
to ferrets.

The timing varies with:
1. Size of implant
2. Reason for use of the implant
3. If disease is present it also varies with the type of
disease, which may range from benign adrenal neoplasia
(common) all the way through to absolutely huge carcinomas.

I do not know if anyone has found much help from it when
lymphoma is in an adrenal. Does anyone have data on that

You'll even find a writeup on an incredibly rare case of a
ferret who did have steroidal effects from an adrenal tumor
who Dr. Schoemaker treated with Suprelorin if you use
Pubmed to find abstracts.

Dr. Nico Schoemaker's articles say that he has seen ferrets
who took as long as 18 to 24 months for symptoms to
reappear, but those are the high figures, not the typical
ones when adrenal disease is present. Also, when symptoms
reappear it can mean that the control slipped a while ago
because for at least some (perhaps many) the control has to
have slipped for a while for the hormonal levels to return
to levels where the symptoms show again.

If your vet knows Dr. Hanneke Moorman then the vet can also
arrange for a consultation, of course. Usually fees for those
are reasonable.

-- Moderator]


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