Message Number: FHL13059 | New FHL Archives Search
From: Sukie Crandall
Date: 2011-03-24 14:04:53 UTC
Subject: [ferrethealth] abstract
To: fhl <>

Some of this will be no surprise to any vet who has had a ferret whose blood coagulated during prep for testing and maybe the article might have info that may be useful for ferrets who have problems with throwing clots.

> J Vet Med Sci. 2011 Mar 18. [Epub ahead of print]
> Comparison of the Blood Coagulation Profiles of Ferrets and Rats.
> Takahashi S, Hirai N, Shirai M, Ito K, Asai F.
> Department of Pharmacology, Azabu University School of Veterinary Medicine.
> Abstract
> The aim of this study was to examine the blood coagulation profiles of ferrets and compare them with those of rats. The ferret activated partial thromboplastin time (aPTT) was slightly longer than the rat aPTT. In contrast, the ferret prothrombin time and thrombin time were profoundly shorter than the corresponding rat values. The fibrinogen level in ferret plasma was two times higher than that in rats. Heparin prolonged all blood coagulation times in a concentration-dependent manner in both ferret and rat plasma. A significantly (P<0.01) higher concentration of heparin was required to double the aPTT in ferrets than rats. These blood coagulation data for ferrets will be useful in experimental animal studies.
> PMID: 21427521 [PubMed - as supplied by publisher]

Sukie (not a vet)

Recommended ferret health links:
all ferret topics:

"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)
On change for its own sake: "You can go really fast if you just jump off the cliff."
(2010, Steve Crandall)


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