Message Number: FHL13079 | New FHL Archives Search
From: Sukie Crandall
Date: 2011-03-30 19:37:11 UTC
Subject: [ferrethealth] abstract
To: fhl <>

100 days of observation is quite long; I wonder if kidney problems related to the paraplegia happened or clots, and if those do happen at a higher rate in paraplegic quadrapeds as they too often sadly do in wheelchair bound bipeds?

> 1. J Am Assoc Lab Anim Sci. 2011;50(2):248-51.
> Recovery from and clearance of rabies virus in a domestic ferret.
> Hamir AN, Niezgoda M, Rupprecht CE.
> Department of Veterinary Medicine and Surgery-Unit 63, MD Anderson Cancer Center,
> Houston, Texas, USA.
> Here we document the case of a domestic ferret (Mustela putorius) that survived
> experimental inoculation with rabies virus of skunk origin. The ferret showed
> initial clinical signs of rabies (hindlimb paralysis) on day 81 after
> inoculation. The animal survived with paraplegia but otherwise was in an adequate
> nutritional state until the end of the observation period (PI day 181). At
> necropsy, no gross lesions were observed. Microscopic lesions were found in
> sections of cerebrum and spinal cord. In both tissues, the lesions were similar
> but were more severe with loss of neuronal parenchyma in the spinal cord. The
> lesions consisted of locally extensive areas with proliferation of astrocytes and
> moderate numbers of glial cells. Severely affected areas also contained clearly
> defined vacuoles in the neuropil. Multifocal areas of involvement showed
> mononuclear cuffing of blood vessels. In a few areas, the cuffing extended to the
> meninges. Rabies virus antigen was not detected by immunohistochemistry of tissue
> sections.
> PMID: 21439220 [PubMed - in process]

Sukie (not a vet)

Recommended ferret health links:
all ferret topics:

"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)
On change for its own sake: "You can go really fast if you just jump off the cliff."
(2010, Steve Crandall)


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