From:
"SukieC"
Date: 2011-04-19 00:42:04 UTC
Subject: [ferrethealth] Re: Osteosarchoma on jaw or sialolith?
To: ferrethealth@yahoogroups.com
How about mineralization in a parotid salivary gland?
http://ferrethealth.org/archive/FHL9657
(In relation to the abstract below which might relate to his problem,
a vet said to me privately that the parotids are less active in ferrets
so might be more vulnerable to mineralization.)
http://ferrethealth.org/archive/FHL9653
> Int J Exp Pathol. 2009 Aug;90(4):439-47.
> Microliths in the parotid of ferret investigated by electron
> microscopy and microanalysis.
> Triantafyllou A, Harrison JD, Garrett JR.
> Oral Pathology, School of Dental Sciences, University of Liverpool,
> Liverpool, UK.
>
> The present investigation is an attempt to determine the occurrence,
> elemental composition and formation of microliths in the parotid of
> ferret. Parotids from four normal ferrets were examined by electron
> microscopy and X-ray microanalysis. Crystalline microliths were
> found in phagosomes of acinar cells, which occasionally contained
> secretory material, and in phagosomes situated between mitochondria
> of striated ductal cells. Crystalline microliths and microliths that
> consisted of granular material either without crystals or mixed with
> a component of crystals were found in lumina, where they were often
> associated with cellular debris. The crystals contained calcium and
> phosphorus. Phagy and stagnation related to pockets of inefficient
> secretory activity have been previously found to be features of the
> parotid of ferret. Thus, possibly persistent degradation of
> redundant cellular material, particularly secretory granules, in
> phagosomes results in accumulation of calcium and leads to calcified
> microliths, whereas consolidation of stagnant debris extracellularly
> does not involve such accumulation and leads to non-calcified or
> mixed microliths.
>
> PMID: 19659902
>
In jaws usually one encounters squamous cell carcinoma or osteoma
but ferrets are always surprising people...
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