Message Number: FHL13145 | New FHL Archives Search
From: "Tressie"
Date: 2011-04-19 16:29:41 UTC
Subject: [ferrethealth] Re: Osteosarchoma on jaw or sialolith?

Here's another reference by the same authors:

Archives of Oral Biology
Volume 52, Issue 8, August 2007, Pages 768-777

doi:10.1016/j.archoralbio.2007.01.010 |

Microenvironmental adaptations in the parotid of ferret investigated by electron microscopy
Asterios Triantafylloua, John D. Harrisonb and John R. Garrettb

aOral Pathology, Department & School of Dental Studies, The University of Liverpool, Liverpool, UK

bDepartment of Oral Pathology, King's College London Dental Institute at Guy's, King's College and St. Thomas' Hospitals, London, UK

Accepted 23 January 2007. Available online 28 February 2007.


Previous histochemical investigations suggested that the microenvironment in the parotid of ferret would foster microlithiasis because of a combination of pockets of inefficient secretion, brisk phagy and secretory material rich in calcium. We have undertaken the present ultrastructural investigation in an attempt to provide corroborative evidence. Parotids from four normal ferrets were examined by electron microscopy. Phagosomes in which there was cellular debris and occasionally secretory granules were present in acinar cells, which indicates crinophagy, and residual bodies were present in ductal cells. Atrophic parenchymal cells, degenerate parenchymal cells and apoptotic bodies were present. Cellular debris and secretory material were present in lumina, which indicates stagnation. The results indicate that removal of redundant secretory material and cells and low flow of saliva are features of the parotid of ferret and support the concept of pockets of inefficient secreto
ry activity.

Keywords: Cell death; Electron microscopy; Macrophages; Parotid; Phagy; Salivary glands; Secretion

Corresponding author at: Pathology Laboratory, Liverpool University Dental Hospital, Pembroke Place, Liverpool L3 5PS, UK. Tel.: +44 151 706 5243; fax: +44 151 706 5845.

Contact info:

Asterios Triantafyllou DipDS, PhD, FRCPath

Title Clinical Lecturer in Oral Pathology

Department School of Dentistry

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