Message Number: FHL13147 | New FHL Archives Search
From: "Tressie"
Date: 2011-04-19 22:29:15 UTC
Subject: [ferrethealth] Re: Non-regenerative Anemia and Reaction to Shots

Hi Susan,

There does appear to be a connection between vaccine reaction and subsequen=
t non-regenerative anemia from observations in veterinary clinical practice=
. Here are some links to articles written by veterinarians that discuss th=
is in animal companions other than ferrets, including specific breeds of do=
gs that appear to be more prone to developing anemia:

And following is a recent case study of a ferret developing severe anemia a=
nd subsequent successful treatment. This is the first known case of PRCA i=
n a ferret.

Immune-mediated pure red cell aplasia in a domestic ferret

Shachar Malka, dvm, dabvp; Michelle G. Hawkins, vmd, dabvp; Shanon M. Zabol=
otzky, dvm, dacvp;
Elizabeth B. Mitchell, ma, dvm, dabvp; Sean D. Owens, dvm, dacvp

Case Description=97An 8-month-old spayed female domestic ferret (Mustela pu=
torius furo)was referred for examination to determine the cause of lethargy=
and severe anemia.
Clinical Findings=97Initial examination revealed that the ferret was lethar=
gic but with appropriate mentation. The only other abnormal findings were s=
evere pallor of the mucous membranes, nasal planum, and skin and a PCV of 8=
%. Pure red cell aplasia(PRCA) was diagnosed on the basis of cytologic eval=
uation of a bone marrow biopsy
Treatment and Outcome=97Medical treatment included blood transfusions, IM a=
dministration of iron dextran, oral administration of antimicrobials and ga=
strointestinal tract protectants,
and SC administration of erythropoietin. Once PRCA was diagnosed, the ferre=
t was orally administered prednisone, cyclosporine, and azathioprine. Nine =
months after onset of treatment, the PRCA was in remission and the ferret w=
as doing well. Immunosuppressive
treatment was discontinued at 14 months after onset of treatment, and 36 mo=
nths after initial examination, the ferret appeared to be healthy.
Clinical Relevance=97It is important that PRCA be considered as a different=
ial diagnosis for a ferret with severe anemia. Prolonged immunosuppressive =
treatment was successful in the ferret described here. (J Am Vet Med Assoc =

Link to this article:

Note the 'Clinical Relevance'in the last paragraph!



Yahoo! Groups Links

<*> To visit your group on the web, go to:

<*> Your email settings:
Individual Email | Traditional

<*> To change settings online go to:
(Yahoo! ID required)

<*> To change settings via email:

<*> To unsubscribe from this group, send an email to:

<*> Your use of Yahoo! Groups is subject to: