Message Number: FHL13148 | New FHL Archives Search
Date: 2011-04-19 23:45:34 UTC
Subject: [ferrethealth] Digest Number 2179

Hi Dario
The only way to know for sure what is going on with that ferret is to
biopsy it and have a pathologist look at it under a microscope.
Hope that helps,
Jerry Murray, DVM

-----Original Message-----
From: ferrethealth <>
To: ferrethealth <>
Sent: Tue, Apr 19, 2011 8:04 am

There are 2 messages in this issue.
Topics in this digest:
1a. Osteosarchoma on jaw or sialolith?=20=20=20
From: Dar=C3=ADo Gentini
b. Re: Osteosarchoma on jaw or sialolith?=20=20=20
From: SukieC

a. Osteosarchoma on jaw or sialolith?
Posted by: "Dar=C3=ADo Gentini" darosaires
Date: Mon Apr 18, 2011 5:31 pm ((PDT))
I'm a veterinary medicine student from Argentina, and work in a clinic that=

reat ferrets.=20
I would like to have the opinion of the FHL in general, and specially Dr. B=
. Williams about a case we've never seen before in our clinic's practice.
The patient is a 3 year old male ferret from Marshall Farms (so neutered an=
The client brought it because saw his jaw wet from saliva. But the Dr. foun=
d a
ass anatomically located on the right mandibular gland. First thought of a=

yst or an abscess, she tried to punctured but it was hard and not movable. =
an only get a few drops of blood from it, and cithology was impossible.
he X-ray showed a roundish mass simillar to bone or a calcificated structur=
e of
aprox 2,5 - 3 cm of diameter, aparently not associated to the jaw but
ithout certainty of it. The x-ray Dr. diagnosis was inclined to say it was=
ialolith, but I repeat, is absolutely impossible to move it.
The size of it is starting to difficult deglution of the ferret, and seems =
to be
growing rapidly. The blood work is fine overall.

lease, I would very much aprecciate any information on how to make a good
iagnosis and proper treatment for each possibility, and prognosis of them. =
ere attach the two x-ray we received.

ith kind regards, from Argentina...

ar=C3=ADo Gentini


Non-text portions of this message have been removed]

essages in this topic (2)
b. Re: Osteosarchoma on jaw or sialolith?
Posted by: "SukieC" sukiedaviscrandall
Date: Mon Apr 18, 2011 5:44 pm ((PDT))

ow about mineralization in a parotid salivary gland?
In relation to the abstract below which might relate to his problem,
vet said to me privately that the parotids are less active in ferrets
o might be more vulnerable to mineralization.)
> Int J Exp Pathol. 2009 Aug;90(4):439-47.
Microliths in the parotid of ferret investigated by electron
microscopy and microanalysis.
Triantafyllou A, Harrison JD, Garrett JR.
Oral Pathology, School of Dental Sciences, University of Liverpool,
Liverpool, UK.

The present investigation is an attempt to determine the occurrence,
elemental composition and formation of microliths in the parotid of
ferret. Parotids from four normal ferrets were examined by electron
microscopy and X-ray microanalysis. Crystalline microliths were
found in phagosomes of acinar cells, which occasionally contained
secretory material, and in phagosomes situated between mitochondria
of striated ductal cells. Crystalline microliths and microliths that
consisted of granular material either without crystals or mixed with
a component of crystals were found in lumina, where they were often
associated with cellular debris. The crystals contained calcium and
phosphorus. Phagy and stagnation related to pockets of inefficient
secretory activity have been previously found to be features of the
parotid of ferret. Thus, possibly persistent degradation of
redundant cellular material, particularly secretory granules, in
phagosomes results in accumulation of calcium and leads to calcified
microliths, whereas consolidation of stagnant debris extracellularly
does not involve such accumulation and leads to non-calcified or
mixed microliths.

PMID: 19659902

In jaws usually one encounters squamous cell carcinoma or osteoma
ut ferrets are always surprising people...

essages in this topic (2)

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