Message Number: FHL13229 | New FHL Archives Search
From: Sukie Crandall
Date: 2011-05-04 23:40:06 UTC
Subject: [ferrethealth] abstracts
To: fhl <>

> Pol J Vet Sci. 2011;14(1):137-9.
> Restoration of fractured canines in ferrets after one-step root canal treatment.
> Bladowski M, Kotowicz-Gears A, Wojtkiewicz J.
> Source
> Department of Human Physiology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, Warszawska 30, 10-082 Olsztyn, Poland.
> Abstract
> This article describes a one-step root canal treatment and restoration of canine teeth in ferrets. Standard brass posts were used for the reconstruction of the teeth. The procedures were performed by dentists according to all rules and procedures used in root canal treatment in humans. The teeth were immediately restored anatomically. The procedures were successfully performed in four ferrets aged between 6 and 20 months of age, in three upper and one lower canines.

> Comp Med. 2011;61(2):145-9.
> Spermatogenesis in ferret testis xenografts: a new model.
> Gourdon JC, Travis AJ.
> Comparative Medicine, McGill University, Montreal, Canada.
> Testis xenografting is both a promising tool to study spermatogenesis and a means
> to preserve the genetic information and reproductive potential of prepubertal
> male animals. The present study was conducted to evaluate this technique using
> testis tissue from domestic ferrets, an important biomedical model and a model
> for the conservation of small carnivore species. Fresh testis tissue from
> 8-wk-old ferrets was implanted ectopically under the skin on the backs of
> castrated nude mice and subsequently evaluated for testosterone production and
> establishment of spermatogenesis at 10, 20, 25, and 30 wk after xenografting. A
> total of 40% of fresh ferret xenografts were harvested. Seminal vesicles were
> collected from the recipient mice and weighed as an assay for bioactive
> testosterone. The weights of seminal vesicles from the mice showed no significant
> difference from those of uncastrated, control nude mice, indicating that the
> xenografts were producing physiologically relevant amounts of testosterone. The
> ferret testis xenografts produced differentiating germ cells and sperm at the
> same time as did testis from age-matched control ferrets. These data demonstrate
> the ability of Mustelidae testicular tissue to establish spermatogenesis in nude
> mice after testis xenografting.
> PMID: 21535925 [PubMed - in process]

> Proc Natl Acad Sci U S A. 2011 May 2. [Epub ahead of print]
> Influenza virus aerosol exposure and analytical system for ferrets.
> Gustin KM, Belser JA, Wadford DA, Pearce MB, Katz JM, Tumpey TM, Maines TR.
> Source
> Influenza Division, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333.
> Abstract
> Understanding the transmission ability of newly emerging influenza viruses is central to the development of public health preparedness and prevention strategies. Animals are used to model influenza virus infection and transmission, but the routinely used intranasal inoculation of a liquid virus suspension does not reflect natural infection. We report the development of an inoculation method that delivers an influenza virus aerosol inoculum to ferrets and the characterization of size distribution and viable virus present in aerosols shed from infected ferrets during normal breathing and sneezing. By comparing virus deposition, infectivity, virulence, and transmissibility among animals inoculated intranasally or by aerosols with a human (H3N2) or avian (H5N1) influenza virus, we demonstrate that aerosol inoculations more closely resemble a natural, airborne influenza virus infection and that viable virus is measurable in droplets and droplet nuclei exhaled by infected ferrets
. These methods will provide improved risk assessment of emerging influenza viruses that pose a threat to public health.
> PMID: 21536880 [PubMed - as supplied by publisher]

Sukie (not a vet)

Recommended ferret health links:
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"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)


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