From:
Sukie Crandall
Date: 2011-06-16 17:26:27 UTC
Subject: Re: [ferrethealth] Re: preputial adenocarcinomas
To: ferrethealth@yahoogroups.com
Okay, that did not make sense to me, either.
In the human work I could see no way it would be a treatment but some ways that it could cause additional problems:
http://www.drugs.com/pro/piroxicam.html
http://www.rxlist.com/feldene-drug.htm
But when I looked at the generic name, Feldene in relation to veterinary I also found this, but notice that it does NOT mention adenocarcinoma which your ferret has (though transitional cell carcinoma get mentioned a lot and I do not know how similar the two are or are not), and malignancies DO vary widely so your vet would need to perhaps ask a veterinary oncologist if it might be a useful addition to treatment and if the possible benefits outweigh the possible risks (which is a calculation that is always made in medicine):
http://www.peteducation.com/article.cfm?c=0+1303+1456&aid=3232
http://www.marvistavet.com/html/piroxicam.html
http://www.oncolink.org/experts/article.cfm?c=3&s=32&ss=86&id=1962
Scroll to transitional cell carcinoma (German Shorthaired Pointer) question from 2000
with the answer that begins:
> Piroxicam (Feldene Rx) is specifically recommended for transitional cell carcinoma due to chemotherapeutic actions that have been described for this medication. I do not know if these actions have been proven or not, but the studies I can find are pretty ambivalent. It is not thought to work very well alone but is often used in combination with chemotherapeutic agents.
>
in
http://www.vetinfo.com/dcarcinoma.html#b
See:
http://ferrethealth.org/archive/SG7269
http://ferrethealth.org/archive/YG13062
Our personal experiences with NSAIDs in ferrets has not been good -- too many times with GI bleeding in ferrets who have never had indications of ulcers or colonic bleeding before-- but individual ferrets do vary a lot, just as humans do.
Resources in here may be useful:
http://ferrethealth.org/archive/FHL1596
On Jun 16, 2011, at 9:32 AM, lesliecucino wrote:
> I was contacted by someone from the FML who suggested using Piroxicam. A quick Google search states that it's a NSAID. She said she thought it was a better alternative to the surgery, but I'm unsure. I did forward the info to my vet, but what is the opinion here? Would Piroxicam stave off just the symptoms, or does it completely suppress the cancer? I guess what I want to know is 'what would you do'?
>
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)
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