Message Number: FHL14493 | New FHL Archives Search
From: "Tressie"
Date: 2012-01-02 23:36:17 UTC
Subject: [ferrethealth] Re: adrenal and increased body temp

Certainly humans with advanced cancers do get what is referred to as a paraneoplastic fever. This occurs most commonly with Hodgkin's lymphoma, acute leukemia, lymphoma, renal cell carcinoma, bone sarcoma, pheochromocytoma and notably, adrenal carcinoma.

Paraneoplastic fever is thought to result from substances produced by the malignant tumors themselves(i.e., inflammatory cytokines). These cytokines cause elevations in core temperature by acting on the hypothalamic temperature setpoint.

A similar mechanism may be operating in ferrets with adrenal carcinoma.



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