Message Number: FHL14598 | New FHL Archives Search
From: Sukie Crandall
Date: 2012-01-25 19:13:10 UTC
Subject: Re: [ferrethealth] Re: a bit more on Neovac

No matter what a person's choices are the final topic addressed in this post will interest you. Have you ever thought that your carpet choice might effect how well your ferrets' vaccines work? See the non-ferret study mentioned in the final part of this post.

Yes, it could really make sense for ferret people in the UK to band together to either get the manufacturers to at least do titer testing at one year after vaccination (preferably, also at least at 6 months), or to have the titers run at their own expense with the results compiled for many ferrets for each of the vaccines tried.

Similarly, anyone here who feels pressed to try a vaccine that is not proven to actually work should also be sure to one way or another have independent titers run by experts (but not so close to the date of vaccination as to be worthless). See the separate FHL Archives to find posts with Cornell in the body to find the one that I happen to know exists. You can link to those archives from the FHL homepage or use the second addy in my sig lines. (BTW, getting titers done at your own expense rather than the manufacturer's expense would make the whole thing more costly than using Purevax which is a proven CDV vaccine for ferrets, but it is still less costly in pain, sadness, veterinary needs, and possible liability needs than using a vaccine not proven to work if that vaccine fails.

And this brings me to some very, very interesting very new studies:

E. Corsini et al. In vitro evaluation of the immunotoxic potential of perfluorinated compounds (PFCs). Toxicology and Applied Pharmacology,Vol. 250, January 15, 2011, p. 108. doi: 10.1016/j.taap.2010.11.004.
P. Grandjean et al. Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. Journal of the American Medical Association,Vol. 307, January 25, 2012, p. 391.
M.M. Peden-Adams et al. Suppression of humoral immunity in mice following exposure to perflulorooctane sulfonate. Toxicological Sciences,Vol. 104, July 2008, p. 144. doi: 10.1093/toxsci/kfn059.

The center one is not noted as being online yet, but here are the other two, and i will check PubMed for the center abstract.

A very good write up on this topic, and notice that it has other links, too:

That article begins:
> Tiny concentrations of two common pollutants — chemicals known as PFOA and PFOS — in the blood may be linked to impaired immunity in children, a new study finds. In kids with the highest exposure to the chemicals, vaccinations can fail to trigger sufficient quantities of protective antibodies.

> When subpar responses occur — antibody levels below 0.1 international units per milliliter — “we can’t rely on a vaccine as being effective,”
> raise questions about whether such deficiencies might also point to a heightened vulnerability to allergy, asthma and even, potentially, autoimmune disease

Notice that ferrets in many households are running around, sleeping, digging, snacking, and living close to carpets treated with such compounds, including Scotchguard, and therefore their vaccines might not work as well, so using some of the precautions to reduce risks that were noted earlier in the discussions on Canine Distemper could be especially important in such homes as could titers.

On Jan 25, 2012, at 5:23 AM, J.Michelle wrote:

> More is the pity there too, as there was a huge outbreak of CDV a few months ago in the4 UK
> --- In, jill perry <jillferretrescue@...> wrote:
> >
> > All CD vaccines used in the UK are dog vaccines - nothing is licensed for ferrets so all are unchallenged.

Sukie (not a vet)

Recommended ferret health links:
all ferret topics:

"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)

[Non-text portions of this message have been removed]


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