Message Number: FHL14930 | New FHL Archives Search
From: Sukie Crandall
Date: 2012-03-10 18:25:58 UTC
Subject: Re: [ferrethealth] Re: Purevax back order?
To: "" <>

If any company is serious about satisfying the needs of the ferret community it could take the next step. For Neovac D WHICH IS *NOT* THE SAME VACCINE THAT DR. RUTH MENTIONED IN HER POST IN THIS DISCUSSION, since it only has one tiny and short safety study in a very few male kits -- so problems like allergic reaction rate remain unknown and effectiveness is unknown -- and cover the costs of vaccines and of a series of titers for some interested parties with ferrets that will not trade hands, with titer results going to the treating veterinarians who then would share them with the company, so that all is above board and reliable for other interested parties. They would need titers done short term but also as far out as a year, and if they went past that time frame then so much the better. The titers should be by an independent and reputable lab which does those tests such as the titer lab at Cornell.

Remember that allergic reactions do NOT tend to happen with first exposure to a substance. The vast majority of allergic reactions happen after many exposures which is why people are most likely to get food allergies to foods they commonly eat and favorite foods. So there are multiple exposures and one of those times the immune system mistakes the okay compound -- usually a protein one -- for an invading infection. Then the NEXT time there is an exposure the allergic reaction happens. Although everyone is aware of childhood allergies and an allergy can begin at any age, in humans the most likely time to develop new allergies is when the immune system is strongest so for people usually that is in the twenties or thirties. Now that you know how allergies develop you can see which years for ferrets might be their times of strongest immune systems, though allergies can begin at any age, and sometimes happen because of an allergy to a shared component or similar enough component in something else having miseducated the immune system.

So, the safety study was not helpful on that regard at all. It did indicate that in the tiny number of male ferrets who got the vaccines in those few weeks of the study there were not side effects and the ferrets did not contract CDV from the vaccine.

The vaccine Dr. Ruth mentions in this discussion is Nobivac DPv which is a descendant vaccine of Galaxy, but the vet should do titers and should make sure each time that they are not using a ferret cell line to grow it if it is live or attentuated virus. I would love to see this one studied more, too, but at least it has some background. BTW, we personally saw more anaphylactic allergic reations with Galaxy than with Purevax, but used the usual precautions when ferrets get vaccines and none were fatal.

The vaccine which has has almost no study except for that one short and tiny study in a few males kits is a different vaccine, Neovac D. There is no way at this point that I would try that without more study, personally, unless it was done with carefully timed multiple titers.

The two names are somewhat similar so DO NOTE THAT THEY ARE TWO DIFFERENT VACCINES.

Sent from my iPad

On Mar 10, 2012, at 11:41 AM, Jeff <> wrote:

> “No adverse reactions” is nice to hear, but are there any studies that show how effective the vaccine actually is??? I’d really like to see some evidence that it works before having it injected it into any of my ferrets

[Non-text portions of this message have been removed]


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